It was only an in-vitro study meaning that it was done on cell cultures and not on real people, but still, this also does not support the use of AP too much. Third, another study that wanted to examine the antioxidant properties of AP was surprised to find that even though AP does have nice antioxidant properties following UVB radiation (the same one that comes from the sun) it also promotes lipid peroxidation and cytotoxicity. We are highly skeptical what effect a tiny amount of AP has in a formula. Even if it can be converted, the palmitate part of the molecule is more than the half of it, so the efficacy will not be good and we have never seen a serum that contains a decent (and proudly disclosed) amount of AP. This does not mean that ascorbyl palmitate cannot penetrate the skin (because it can, it's oil soluble and the skin likes to absorb oil soluble things) but this means that it's questionable if ascorbyl palmitate can be converted into pure Vit C in the skin. Second, a study that examined the skin absorption of vitamin C found that ascorbyl palmitate did not increase the skin levels of AA. A great study in the Journal of Cosmetic Dermatology compared a bunch of vitamin C derivatives and this derivative was the only one where the study said in terms of stability that it's "similar to AA". Firstly, it's stability is only similar to that of pure ascorbic acid (AA), which means it is not really stable.
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